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概 述
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Full name: |
proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane) |
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Synonyms: |
TMG3; PRGP3 |
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Swissprot: |
Q9BZD7 |
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Gene Accession: |
BC128256 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
PRRG3 (proline-rich gamma-carboxyglutamic acid protein 3), also known as TMG3 (transmembrane gamma-carboxyglutamic acid protein 3) or PRGP3, is a 231 amino acid single-pass type I membrane protein found in kidney, heart and brain. PRRG3 contains an N-terminal Gla (gamma-carboxy-glutamate) domain, two PPXY motifs and is encoded by a gene that maps to human chromosome Xq28. Chromosome X consists of about 153 million base pairs and nearly 1,000 genes. Color blindness, hemophilia and Duchenne muscular dystrophy are well known X chromosome-linked conditions which affect males more frequently, as males carry a single X chromosome. |
