小鼠抗ALDOA单克隆抗体

Background:

This gene encodes a member of the class I fructose-bisphosphate aldolase protein family. The encoded protein is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Mutations in this gene have been associated with Glycogen Storage Disease XII, an autosomal recessive disorder associated with hemolytic anemia. Disruption of this gene also plays a role in the progression of multiple types of cancers. Related pseudogenes have been identified on chromosomes 3 and 10.

Applications:

ELISA, WB

Name of antibody:

ALDOA

Immunogen:

Fusion protein of human ALDOA

Full name:

aldolase, fructose-bisphosphate A

Synonyms:

ALDA; GSD12; HEL-S-87p; Aldolase A

SwissProt:

P04075

WB Predicted band size:

39 kDa

WB Positive control:

HeLa, HepG2, NIH/3T3, 293T, 231, A549 and HT-29 cell lysates

WB Recommended dilution:

500-2000