兔抗IL2RB多克隆抗体

Background:

The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein.

Applications:

ELISA, WB, IHC

Name of antibody:

IL2RB

Immunogen:

Fusion protein of human IL2RB

Full name:

interleukin 2 receptor, beta

Synonyms：

CD122; IL15RB; P70-75

SwissProt:

P14784

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human thyroid cancer and human cervical cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

61 kDa

WB Positive control:

231, 293T, Raji and hela cells

WB Recommended dilution:

500-2000