小鼠抗TH单克隆抗体

Background:

The protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Applications:

WB, IF

Name of antibody:

TH

Immunogen:

Fusion protein of human TH

Full name:

tyrosine hydroxylase (TH), transcript variant 2

Synonyms:

DYT14; DYT5b; TYH

SwissProt:

P07101

WB Predicted band size:

59 kDa

WB Positive control:

HepG2, Hela, SVT2, A549, COS7, Jurkat, MDCK, PC12, MCF-7 cell lysates

WB Recommended dilution:

500-2000