兔抗IBSP多克隆抗体

Background:

The protein encoded by this gene is a major structural protein of the bone matrix. It constitutes approximately 12% of the noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor.

Applications:

ELISA, IHC

Name of antibody:

IBSP

Immunogen:

Synthetic peptide of human IBSP

Full name:

integrin-binding sialoprotein

Synonyms：

BSP; BNSP; SP-II; BSP-II

SwissProt:

P21815

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human breast cancer and Human colon cancer

IHC Recommend dilution:

25-100