兔抗IBA57多克隆抗体

Background:

The protein encoded by this gene localizes to the mitochondrion and is part of the iron-sulfur cluster assembly pathway. The encoded protein functions late in the biosynthesis of mitochondrial 4Fe-4S proteins. Defects in this gene have been associated with autosomal recessive spastic paraplegia-74 and with multiple mitochondrial dysfunctions syndrome-3. Two transcript variants encoding different isoforms have been found for this gene. The smaller isoform is not likely to be localized to the mitochondrion since it lacks the amino-terminal transit peptide.

Applications:

ELISA, IHC

Name of antibody:

IBA57

Immunogen:

Synthetic peptide of human IBA57

Full name:

IBA57 homolog, iron-sulfur cluster assembly

Synonyms:

MMDS3; SPG74; C1orf69

SwissProt:

Q5T440

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human ovarian cancer and human brain

IHC Recommend dilution:

30-150