兔抗FKBP3多克隆抗体

Background:

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.

Applications:

ELISA, WB, IHC

Name of antibody:

FKBP3

Immunogen:

Fusion protein of human FKBP3

Full name:

FKBP prolyl isomerase 3

Synonyms:

FKBP-3; FKBP25; PPIase; FKBP-25

SwissProt:

Q00688

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer

IHC Recommend dilution:

200-300

WB Predicted band size:

25 kDa

WB Positive control:

Human bladder transitional cell carcinoma grade 2-3 tissue, Human bladder transitional cell carcinoma cancer next level 2-3 tissue lysate

WB Recommended dilution:

1000-5000