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Background: |
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling pathways. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes an alpha subunit and belongs to the G-alpha family. Mutation in this gene, resulting in a gly40-to-arg substitution, is associated with auriculocondylar syndrome, and shown to affect downstream targets in the G protein-coupled endothelin receptor pathway. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
GNAI3 |
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Immunogen: |
Fusion protein of human GNAI3 |
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Full name: |
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 |
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Synonyms: |
87U6; ARCND1 |
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SwissProt: |
P08754 |
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ELISA Recommended dilution: |
1000-2000 |
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IHC positive control: |
Human lung cancer |
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IHC Recommend dilution: |
25-100 |

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