Background: 
					 
						The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified. 
					 
						Applications: 
					 
						ELISA, WB, IHC 
					 
						Name of antibody: 
					 
						HTR3A 
					 
						Immunogen: 
					 
						Fusion protein of human HTR3A 
					 
						Full name: 
					 
						5-hydroxytryptamine receptor 3A 
					 
						Synonyms: 
					 
						HTR3; 5HT3R; 5-HT-3; 5-HT3A; 5-HT3R 
					 
						SwissProt: 
					 
						P46098 
					 
						ELISA Recommended dilution: 
					 
						5000-10000 
					 
						IHC positive control: 
					 
						Human tonsil 
					 
						IHC Recommend dilution: 
					 
						40-200 
					 
						WB Predicted band size: 
					 
						55 kDa 
					 
						WB Positive control: 
					 
						TM4 cell lysate 
					 
						WB Recommended dilution: 
					 
						200-1000 
					
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