兔抗HTR3A多克隆抗体

Background:

The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified.

Applications:

ELISA, WB, IHC

Name of antibody:

HTR3A

Immunogen:

Fusion protein of human HTR3A

Full name:

5-hydroxytryptamine receptor 3A

Synonyms:

HTR3; 5HT3R; 5-HT-3; 5-HT3A; 5-HT3R

SwissProt:

P46098

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human tonsil

IHC Recommend dilution:

40-200

WB Predicted band size:

55 kDa

WB Positive control:

TM4 cell lysate

WB Recommended dilution:

200-1000