抗 原: HSD3B7
储 存: 冷冻(-20℃)
反应种属: Human, Mouse, Rat
标 记 物: Unconjugate
技术规格
| Background: | This gene encodes an enzyme which is involved in the initial stages of the synthesis of bile acids from cholesterol and a member of the short-chain dehydrogenase/reductase superfamily. The encoded protein is a membrane-associated endoplasmic reticulum protein which is active against 7-alpha hydrosylated sterol substrates. Mutations in this gene are associated with a congenital bile acid synthesis defect which leads to neonatal cholestasis, a form of progressive liver disease. Multiple transcript variants encoding different isoforms have been found for this gene. | 
| Applications: | ELISA, IHC | 
| Name of antibody: | HSD3B7 | 
| Immunogen: | Fusion protein of human HSD3B7 | 
| Full name: | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 | 
| Synonyms: | CBAS1; PFIC4; SDR11E3 | 
| SwissProt: | Q9H2F3 | 
| ELISA Recommended dilution: | 2000-5000 | 
| IHC positive control: | Human prostate cancer and human brain | 
| IHC Recommend dilution: | 50-200 | 


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