兔抗Histone H3(Phospho-Ser28)多克隆抗体

Background:

Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.

Applications:

WB

Name of antibody:

Histone H3(Phospho-Ser28)

Immunogen:

Peptide sequence around phosphorylation site of serine 28(R-K-S(p)-A-P) derived from Human Histone H3

Full name:

Histone H3

Synonyms:

H3/A; H3FA

SwissProt:

P68431

WB Predicted band size:

15 kDa

WB Positive control:

Hela cells lysates treated with Nocodazole (1μg/ml, 24 hrs)

WB Recommended dilution:

200-500