兔抗HK1多克隆抗体

Background:

Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in five transcript variants which encode different isoforms, some of which are tissue-specific. Each isoform has a distinct N-terminus; the remainder of the protein is identical among all the isoforms.

Applications:

ELISA, WB, IHC

Name of antibody:

HK1

Immunogen:

Fusion protein of human HK1

Full name:

hexokinase 1

Synonyms：

HKD; HKI; HXK1; HMSNR; HK1-ta; HK1-tb; HK1-tc

SwissProt:

P19367

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human thyroid cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

102 kDa

WB Positive control:

231 cell

WB Recommended dilution:

200-1000