兔抗HIST1H4A(Phospho-Lys5) 多克隆抗体

Background:

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures.

Applications:

WB

Name of antibody:

HIST1H4A(Phospho-Lys5)

Immunogen:

Peptide sequence around acetylation site of Lysine 5 (S-G-R(p)-G-K) derived from Human Histone H4.

Full name:

histone cluster 2, H4a

Synonyms：

H4; H4/n; H4F2; H4FN; FO108; HIST2H4

SwissProt:

P62805

WB Predicted band size:

11 kDa

WB Positive control:

COS7 cells lysates untreated or treated with TSA

WB Recommended dilution:

500-1000