兔抗CASR(Phospho-Thr888)多克隆抗体

Background:

The protein encoded by this gene is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis.

Applications:

WB

Name of antibody:

CASR(Phospho-Thr888)

Immunogen:

Peptide sequence around phosphorylation site of Threonine 888 (R-A-T(p)-L-R) derived from Human Calcium Sensing Receptor.

Full name:

calcium-sensing receptor

Synonyms：

CAR; FHH; FIH; HHC; EIG8; HHC1; NSHPT; PCAR1; GPRC2A; HYPOC1

SwissProt:

P41180

WB Predicted band size:

121 kDa

WB Positive control:

LOVO cells lysates

WB Recommended dilution:

500-1000