兔抗CLDN3多克隆抗体

IHC Recommend dilution:

25-100

IHC positive control:

Human breast cancer and Human colon cancer

ELISA Recommended dilution:

1000-10000

SwissProt:

O15551

Synonyms：

RVP1, HRVP1, C7orf1, CPE-R2, CPETR3

Full name:

claudin 3

Immunogen:

Synthetic peptide of human CLDN3

Name of antibody:

CLDN3

Applications:

ELISA, IHC

Background:

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat.