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Background: |
Serine/threonine-protein kinase that acts as a regulator of the p38/MAPK14 stress-activated MAPK cascade and of the MAPK8/JNK cascade. Acts as an activator of the p38/MAPK14 stress-activated MAPK cascade. In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of upstream MAP2K3 and MAP2K6 kinases. Inhibits basal activity of MAPK8/JNK cascade and diminishes its activation in response epidermal growth factor (EGF). |
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Applications: |
WB |
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Name of antibody: |
TAOK3 |
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Immunogen: |
Synthesized peptide derived from internal of human TAOK3. |
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Full name: |
TAO kinase 3 |
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Synonyms： |
DPK; JIK; MAP3K18 |
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SwissProt: |
Q9H2K8 |
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WB Predicted band size: |
105 kDa |
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WB Positive control: |
K562 cells lysate |
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WB Recommended dilution: |
500-3000 |
