小鼠抗IL1A单克隆抗体

Background:

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease.

Applications:

WB, IF

Name of antibody:

IL1A

Immunogen:

Fusion protein of human IL1A

Full name:

interleukin 1, alpha (IL1A)

Synonyms:

IL-1A; IL1; IL1-ALPHA; IL1F1

SwissProt:

P01583

WB Predicted band size:

31 kDa

WB Positive control:

HepG2, Hela, A549, COS7, Jurkat, MDCK, MCF-7 cell lysates

WB Recommended dilution:

200-1000