小鼠抗FOS单克隆抗体

Background:

The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death. [provided by RefSeq, Jul 2008].

Applications:

WB, IHC

Name of antibody:

FOS

Immunogen:

Fusion protein of human FOS

Full name:

FBJ murine osteosarcoma viral oncogene homolog (FOS)

Synonyms:

AP-1; C-FOS; p55

SwissProt:

P01100

IHC positive control:

human liver tissue and carcinoma of human liver tissue; adenocarcinoma of human endometrium tissue

IHC Recommend dilution:

30-150

WB Predicted band size:

41 kDa

WB Positive control:

HepG2, Hela, SVT2, A549, COS7 cell lysates

WB Recommended dilution:

200-1000