小鼠抗CRLF3单克隆抗体

Background:

This gene encodes a cytokine receptor-like factor that may negatively regulate cell cycle progression at the G0/G1 phase. Studies of the related rat protein suggest that it may regulate neuronal morphology and synaptic vesicle biogenesis. This gene is one of several genes located in the neurofibromatosis type I tumor suppressor region on the q arm of chromosome 17, a region that is subject to microdeletions, duplications, chromosomal breaks and rearrangements. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 2 and 5.

Applications:

WB, IHC

Name of antibody:

CRLF3

Immunogen:

Fusion protein of human CRLF3

Full name:

cytokine receptor like factor 3

Synonyms:

FRWS; CRLM9; p48.2; CREME9; CYTOR4; CREME-9

SwissProt:

Q8IUI8

IHC positive control:

Human spleen tissue

IHC Recommend dilution:

500-2000

WB Predicted band size:

50 KD

WB Positive control:

NCI-H460 cell lysate

WB Recommended dilution:

200-1000