小鼠抗GRB7单克隆抗体

Background:

The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with epidermal growth factor receptor (EGFR) and ephrin receptors. The protein plays a role in the integrin signaling pathway and cell migration by binding with focal adhesion kinase (FAK). Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]

Applications:

WB

Name of antibody:

GRB7

Immunogen:

Fusion protein of human GRB7

Full name:

growth factor receptor bound protein 7

SwissProt:

Q14451

WB Predicted band size:

60 KD

WB Positive control:

Hela, HepG2, COLO205, A431 cell, Mouse spleen tissue lysates

WB Recommended dilution:

500-2000