小鼠抗FASN单克隆抗体

Background:

The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.

Applications:

WB, IP, IF

Name of antibody:

FASN

Immunogen:

Fusion protein of human FASN

Full name:

fatty acid synthase

Synonyms:

FAS; OA-519; SDR27X1

SwissProt:

P49327

WB Predicted band size:

273 kDa

WB Positive control:

Hela, C6, 3T3, CHO-K1 and 293 cell lysates

WB Recommended dilution:

1000-5000

IF positive control:

Hela cells

IF Recommend dilution:

200-400