小鼠抗POLR2J2单克隆抗体

Background:

This gene is a member of the RNA polymerase II subunit 11 gene family, which includes three genes in a cluster on chromosome 7q22.1 and a pseudogene on chromosome 7p13. The founding member of this family, DNA directed RNA polymerase II polypeptide J, has been shown to encode a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This locus produces multiple, alternatively spliced transcripts that potentially express isoforms with distinct C-termini compared to DNA directed RNA polymerase II polypeptide J. Most or all variants are spliced to include additional non-coding exons at the 3' end which makes them candidates for nonsense-mediated decay (NMD). Consequently, it is not known if this locus expresses a protein or proteins in vivo. [provided by RefSeq].

Applications:

WB

Name of antibody:

POLR2J2

Immunogen:

Fusion protein of human POLR2J2

Full name:

polymerase (RNA) II (DNA directed) polypeptide J2 (POLR2J2)

Synonyms:

HRPB11B; RPB11b1

SwissProt:

Q9GZM3

WB Predicted band size:

13 kDa

WB Positive control:

HepG2, Hela, HT-29, A549, COS7, Jurkat, MDCK, PC12, MCF-7 cell lysates

WB Recommended dilution:

1000-5000