小鼠抗ENG单克隆抗体

Background:

This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008].

Applications:

WB, IF

Name of antibody:

ENG

Immunogen:

Fusion protein of human ENG

Full name:

endoglin (ENG), transcript variant 2

Synonyms:

END; HHT1; ORW1

SwissProt:

P17813

WB Predicted band size:

71 kDa

WB Positive control:

HepG2, Hela, SVT2, A549, COS7, Jurkat, MDCK, PC12, MCF-7 cell lysates

WB Recommended dilution:

500-2000