兔抗ABCA1多克隆抗体

Background:

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in this gene have been associated with Tangier's disease and familial high-density lipoprotein deficiency.

Applications:

ELISA, WB, IHC

Name of antibody:

ABCA1

Immunogen:

Synthetic peptide of human ABCA1

Full name:

ATP binding cassette subfamily A member 1

Synonyms:

TGD; ABC1; CERP; ABC-1; HDLDT1

SwissProt:

O95477

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human esophagus cancer

IHC Recommend dilution:

50-100

WB Predicted band size:

254 kDa

WB Positive control:

Human bladder transitional cell carcinoma grade 2-3 tissue, Human bladder transitional cell carcinoma cancer next level 2-3 tissue lysates

WB Recommended dilution:

200-1000