兔抗CLOCK多克隆抗体

Background:

The protein encoded by this gene plays a central role in the regulation of circadian rhythms. The protein encodes a transcription factor of the basic helix-loop-helix (bHLH) family and contains DNA binding histone acetyltransferase activity. The encoded protein forms a heterodimer with ARNTL (BMAL1) that binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes.

Applications:

WB, IHC

Name of antibody:

CLOCK

Immunogen:

Synthesized peptide derived from Internal of human Clock.

Full name:

clock circadian regulator

Synonyms：

KAT13D; bHLHe8

SwissProt:

O15516

IHC positive control:

Human skeletal muscle tissue

IHC Recommend dilution:

50-100

WB Predicted band size:

95 kDa

WB Positive control:

Huvec cells lysate

WB Recommended dilution:

500-3000