小鼠抗CHD4单克隆抗体

Background:

The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. Somatic mutations in this gene are associated with serous endometrial tumors. Alternative splicing results in multiple transcript variants encoding different isoforms.

Applications:

WB, IP

Name of antibody:

CHD4

Immunogen:

Fusion protein of human CHD4

Full name:

chromodomain helicase DNA binding protein 4

Synonyms:

CHD-4; Mi-2b; SIHIWES; Mi2-BETA

SwissProt:

Q14839

WB Predicted band size:

218 kDa

WB Positive control:

293, Jurkat, MOLT-4, HL-60, HelaNE and K562 cell lysates

WB Recommended dilution:

1000-5000