小鼠抗CCT4单克隆抗体

Background:

The chaperonin containing TCP1 (MIM 186980) complex (CCT), also called the TCP1 ring complex, consists of 2 back-to-back rings, each containing 8 unique but homologous subunits, such as CCT4. CCT assists the folding of newly translated polypeptide substrates through multiple rounds of ATP-driven release and rebinding of partially folded intermediate forms. Substrates of CCT include the cytoskeletal proteins actin (see MIM 102560) and tubulin (see MIM 191130), as well as alpha-transducin (MIM 139330) (Won et al., 1998 [PubMed 9819444]).[supplied by OMIM, Mar 2008]

Applications:

WB

Name of antibody:

CCT4

Immunogen:

Fusion protein of human CCT4

Full name:

chaperonin containing TCP1 subunit 4

Synonyms:

SRB; Cctd; CCT-DELTA

SwissProt:

P50991

WB Predicted band size:

58 KD

WB Positive control:

K562, 293T, MCF7, Hela, PC3, HepG2, A549, H460, COLO205 cell lysates

WB Recommended dilution:

500-2000