兔抗CEP170多克隆抗体

Background:

The product of this gene is a component of the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. During interphase, the encoded protein localizes to the sub-distal appendages of mature centrioles, which are microtubule-based structures thought to help organize centrosomes. During mitosis, the protein associates with spindle microtubules near the centrosomes. The protein interacts with and is phosphorylated by polo-like kinase 1, and functions in maintaining microtubule organization and cell morphology. The human genome contains a putative transcribed pseudogene. Several alternatively spliced transcript variants of this gene have been found, but the full-length nature of some of these variants has not been determined.

Applications:

ELISA, WB, IHC

Name of antibody:

CEP170

Immunogen:

Synthetic peptide of human CEP170

Full name:

centrosomal protein 170

Synonyms:

KAB; FAM68A; KIAA0470

SwissProt:

Q5SW79

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer

IHC Recommend dilution:

10-50

WB Predicted band size:

175 kDa

WB Positive control:

PC-3 cell lysate

WB Recommended dilution:

200-1000