兔抗LATS2多克隆抗体

Background:

This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression.

Applications:

ELISA, IHC

Name of antibody:

LATS2

Immunogen:

Synthetic peptide of human LATS2

Full name:

large tumor suppressor kinase 2

Synonyms：

KPM

SwissProt:

Q9NRM7

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human thyroid cancer and Human liver cancer

IHC Recommend dilution:

25-100