小鼠抗APOA5单克隆抗体

Background:

The protein encoded by this gene is an apolipoprotein that plays an important role in regulating the plasma triglyceride levels, a major risk factor for coronary artery disease. It is a component of high density lipoprotein and is highly similar to a rat protein that is upregulated in response to liver injury. Mutations in this gene have been associated with hypertriglyceridemia and hyperlipoproteinemia type 5. This gene is located proximal to the apolipoprotein gene cluster on chromosome 11q23. Alternatively spliced transcript variants encoding the same protein have been identified.

Applications:

WB, IF

Name of antibody:

APOA5

Immunogen:

Fusion protein of human APOA5

Full name:

apolipoprotein A-V (APOA5), transcript variant 1

Synonyms:

APOAV; RAP3

SwissProt:

Q6Q788

WB Predicted band size:

41 kDa

WB Positive control:

HepG2, Hela, SVT2, A549, COS7, Jurkat, MDCK, PC12, MCF-7 cell lysates

WB Recommended dilution:

1000-5000