兔抗ADAMTS2多克隆抗体

Background:

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature procollagen N-proteinase. This proteinase excises the N-propeptide of the fibrillar procollagens types I-III and type V. Mutations in this gene cause Ehlers-Danlos syndrome type VIIC, a recessively inherited connective-tissue disorder. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

Applications:

ELISA, IHC

Name of antibody:

ADAMTS2

Immunogen:

Synthetic peptide of human ADAMTS2

Full name:

ADAM metallopeptidase with thrombospondin type 1 motif 2

Synonyms:

NPI; PNPI; PCINP; PCPNI; PCI-NP; PC I-NP; ADAM-TS2; ADAMTS-2; ADAMTS-3; EDSDERMS

SwissProt:

O95450

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human tonsil and Human colorectal cancer

IHC Recommend dilution:

30-150