小鼠抗ACSF2单克隆抗体

Background:

ACSF2 (acyl-CoA synthetase family member 2), also known as PPAR binding, long chain fatty acid acyl Co-A ligase like, is a 615 amino acid protein belonging to the ATP-dependent AMP-binding enzyme family. Encoded by a gene that maps to human chromosome 17q21.33, ACSF2 contains a PPAR -recognition element in its promoter sequence. Exhibiting mitochondrial subcellular localization, ACSF2 forms a thioester with CoA, thereby catalyzing the initial reaction in fatty acid metabolism. ACSF2 participates in ATP binding, ligase activity and adipodyte differentiation, and displays a preference for medium-chain substrates. ACSF2 may be a potential prognostic molecular marker for breast cancer.

Applications:

WB, IHC, IF, FC

Name of antibody:

ACSF2

Immunogen:

Fusion protein of human ACSF2

Full name:

acyl-CoA synthetase family member 2 (ACSF2), transcript variant 2

Synonyms:

ACSMW; AVYV493

SwissProt:

Q96CM8

IHC positive control:

carcinoma of human lung tissue and carcinoma of human thyroid tissue

IHC Recommend dilution:

30-150

WB Predicted band size:

68 kDa

WB Positive control:

HepG2, MCF-7 cell lysates

WB Recommended dilution:

200-1000