兔抗CFL1/2多克隆抗体

Background:

Binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity. Regulates actin cytoskeleton dynamics. Important for normal progress through mitosis and normal cytokinesis. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required for the up-regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation.

Applications:

WB

Name of antibody:

CFL1/2

Immunogen:

Synthesized peptide derived from internal of human Cofilin.

Full name:

cofilin 1 (non-muscle)/2 (muscle)

Synonyms：

CFL; HEL-S-15/NEM7

SwissProt:

P23528/Q9Y281

WB Predicted band size:

19 kDa

WB Positive control:

Jurkat cells and Hela cells lysates

WB Recommended dilution:

500-3000