兔抗ITGA5多克隆抗体

Background:

The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.

Applications:

ELISA, IHC

Name of antibody:

ITGA5

Immunogen:

Fusion protein of human ITGA5

Full name:

integrin subunit alpha 5

Synonyms:

FNRA; CD49e; VLA-5; VLA5A

SwissProt:

P08648

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human colorectal cancer

IHC Recommend dilution:

25-100