兔抗CFL2多克隆抗体

Background:

This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. This protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH-dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants.

Applications:

ELISA, WB, IHC

Name of antibody:

CFL2

Immunogen:

Synthetic peptide of human CFL2

Full name:

cofilin 2

Synonyms:

NEM7

SwissProt:

Q9Y281

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer and human lung cancer

IHC Recommend dilution:

20-100

WB Predicted band size:

19 kDa

WB Positive control:

Raji cell，Rat skeletal muscle tissue，Hela cell，Mouse skeletal muscle tissue and Mouse brain tissue lysates

WB Recommended dilution:

200-1000