兔抗MUC1(Phospho-Tyr1229)多克隆抗体

Background:

This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex.

Applications:

WB, IHC, IF

Name of antibody:

MUC1(Phospho-Tyr1229)

Immunogen:

Peptide sequence around phosphorylation site of tyrosine 1229 S-P-Y(p)-E-K) derived from Human CD227/MUC1.

Full name:

mucin 1, cell surface associated

Synonyms：

EMA; MCD; PEM; PUM; KL-6; MAM6; MCKD; PEMT; CD227; H23AG; MCKD1; MUC-1; ADMCKD; ADMCKD1; CA 15-3; MUC-1/X; MUC1/ZD; MUC-1/SEC

SwissProt:

P15941

IHC positive control:

Human breast carcinoma tissue

IHC Recommend dilution:

50-100

WB Predicted band size:

122 kDa

WB Positive control:

HepG2 cells lysates treated with PMA

WB Recommended dilution:

500-1000

IF positive control:

HepG2 cells

IF Recommend dilution:

100-200