兔抗CEBPB多克隆抗体

Background:

The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene.

Applications:

ELISA, IHC

Name of antibody:

CEBPB

Immunogen:

Synthetic peptide of human CEBPB

Full name:

CCAAT/enhancer binding protein (C/EBP), beta

Synonyms：

LAP; CRP2; TCF5; IL6DBP; NF-IL6; C/EBP-beta

SwissProt:

P17676

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human thyroid cancer and Human brain

IHC Recommend dilution:

50-200