兔抗CEBPA多克隆抗体

Background:

The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. The encoded protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, the encoded protein can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells.

Applications:

ELISA, IHC

Name of antibody:

CEBPA

Immunogen:

Synthetic peptide of human CEBPA

Full name:

CCAAT/enhancer binding protein (C/EBP), alpha

Synonyms：

CEBP, C/EBP-alpha

SwissProt:

P49715

ELISA Recommended dilution:

2000-10000

IHC positive control:

Human tonsil and Human ovarian cancer

IHC Recommend dilution:

50-200