兔抗ZNF85多克隆抗体

Background:

Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF85 (Zinc finger protein 85), also known as zinc finger protein HPF4 or HTF1, is a member of the ZNF91 family and is thought to be involved in transcriptional regulation. ZNF85 is highly expressed in testicular tissue and localizes to the nucleus. ZNF85 contains sixteen C2H2-type zinc fingers and one KRAB domain through which it is thought to be involved in DNA-binding and transcriptional regulation.

Applications:

ELISA, WB, IHC

Name of antibody:

ZNF85

Immunogen:

Synthetic peptide of human ZNF85

Full name:

zinc finger protein 85

Synonyms:

HPF4; HTF1

SwissProt:

Q03923

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human thyroid cancer

IHC Recommend dilution:

20-100

WB Predicted band size:

69 kDa

WB Positive control:

Raji and PC3 cell lysates

WB Recommended dilution:

500-2000