兔抗ARNT2多克隆抗体

Background:

This gene encodes a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. The encoded protein acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions, the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. A highly similar protein in mouse forms functional complexes with both aryl hydrocarbon receptors and Single-minded proteins, suggesting additional roles for the encoded protein in the metabolism of xenobiotic compounds and the regulation of neurogenesis, respectively.

Applications:

WB

Name of antibody:

ARNT2

Immunogen:

Synthesized peptide derived from internal of human ARNT2.

Full name:

aryl-hydrocarbon receptor nuclear translocator 2

Synonyms：

WEDAS; bHLHe1

SwissProt:

Q9HBZ2

WB Predicted band size:

79 kDa

WB Positive control:

Jurkat cells and 293 cells lysates

WB Recommended dilution:

500-3000