兔抗CDH13多克隆抗体

Background:

This gene encodes a member of the cadherin superfamily. The encoded protein is localized to the surface of the cell membrane and is anchored by a GPI moiety, rather than by a transmembrane domain. The protein lacks the cytoplasmic domain characteristic of other cadherins, and so is not thought to be a cell-cell adhesion glycoprotein. This protein acts as a negative regulator of axon growth during neural differentiation. It also protects vascular endothelial cells from apoptosis due to oxidative stress, and is associated with resistance to atherosclerosis. The gene is hypermethylated in many types of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.

Applications:

WB

Name of antibody:

CDH13

Immunogen:

Fusion protein of human CDH13

Full name:

cadherin 13, H-cadherin (heart)

Synonyms：

CDHH; P10

SwissProt:

P55290

WB Predicted band size:

78 kDa

WB Positive control:

Mouse heart tissue

WB Recommended dilution:

500-2000