兔抗DOK1多克隆抗体

Background:

The protein encoded by this gene is part of a signal transduction pathway downstream of receptor tyrosine kinases. The encoded protein is a scaffold protein that helps form a platform for the assembly of multiprotein signaling complexes. Two transcript variants encoding different isoforms have been found for this gene. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3.

Applications:

ELISA, WB

Name of antibody:

DOK1

Immunogen:

Fusion protein of human DOK1

Full name:

docking protein 1, 62kDa (downstream of tyrosine kinase 1)

Synonyms：

P62DOK

SwissProt:

Q99704

ELISA Recommended dilution:

2000-5000

WB Predicted band size:

52 kDa

WB Positive control:

Human hepatocellsular carcinoma tissue and Jurkat cells

WB Recommended dilution:

500-2000