兔抗CD27多克隆抗体

Background:

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.

Applications:

ELISA, WB, IHC

Name of antibody:

CD27

Immunogen:

Fusion protein of human CD27

Full name:

CD27 molecule

Synonyms：

T14; S152; Tp55; TNFRSF7; S152. LPFS2

SwissProt:

P26842

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human colon cancer and human thyroid cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

29 kDa

WB Positive control:

Raji and lovo cells

WB Recommended dilution:

500-2000