兔抗CCNJ多克隆抗体

Background:

Cyclin J is a 372 amino acid protein encoded by the human gene CCNJ located on chromosome 10. Cyclin J belongs to the cyclin family and contains one cyclin N-terminal domain. A cyclin forms a complex with its partner cyclin-dependent kinase (Cdk), which activates the protein kinase function of the Cdk. Cyclins are so named because their concentration varies in a cyclical fashion during the cell cycle. They are produced or degraded as needed in order to drive the cell through the different stages of the cell cycle. When its concentrations in the cell are low, the cyclin detaches from the Cdk, inhibiting the activity of the enzyme, probably by causing a protein chain to block the enzymatic site. Cyclin J-associated kinase activity is required for the early embryonic division cycles.

Applications:

ELISA, WB, IHC

Name of antibody:

CCNJ

Immunogen:

Synthetic peptide of human CCNJ

Full name:

cyclin J

Synonyms:

bA690P14.1

SwissProt:

Q5T5M9

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human gastric cancer;

IHC Recommend dilution:

10-50

WB Predicted band size:

43 kDa

WB Positive control:

K562 cell lysate

WB Recommended dilution:

200-1000