兔抗MADCAM1多克隆抗体

Background:

The protein encoded by this gene is an endothelial cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM-1 (alpha4beta7), L-selectin, and VLA-4 (alpha4beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues. It is a member of the immunoglobulin family and is similar to ICAM1 and VCAM1. At least seven alternatively spliced transcripts encoding different protein isoforms have been found for this gene, but the full-length nature of some variants has not been determined.

Applications:

ELISA, WB, IHC

Name of antibody:

MADCAM1

Immunogen:

Synthetic peptide of human MADCAM1

Full name:

mucosal vascular addressin cell adhesion molecule 1

Synonyms:

MACAM1

SwissProt:

Q13477

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer

IHC Recommend dilution:

50-100

WB Predicted band size:

40 kDa

WB Positive control:

Mouse liver tissue lysate

WB Recommended dilution:

500-2000