兔抗CBFA2T3多克隆抗体

Background:

This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(16;21)(q24;q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. This gene is also a putative breast tumor suppressor. Alternative splicing results in transcript variants.

Applications:

ELISA, IHC

Name of antibody:

CBFA2T3

Immunogen:

Synthetic peptide of human CBFA2T3

Full name:

CBFA2/RUNX1 translocation partner 3

Synonyms:

ETO2; MTG16; MTGR2; ZMYND4; RUNX1T3

SwissProt:

O75081

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human thyroid cancer

IHC Recommend dilution:

30-150