兔抗AFP多克隆抗体

Background:

This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.

Applications:

ELISA, WB, IHC

Name of antibody:

AFP

Immunogen:

Fusion protein of human AFP

Full name:

alpha-fetoprotein

Synonyms：

FETA, HPAFP

SwissProt:

P02771

ELISA Recommended dilution:

2000-10000

IHC positive control:

Human liver cancer and Human tonsil

IHC Recommend dilution:

50-200

WB Predicted band size:

69 kDa

WB Positive control:

Human liver cancer tissue

WB Recommended dilution:

1000-5000