兔抗SENP5多克隆抗体

Background:

The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for numerous biologic processes. SUMO-specific proteases, such as SENP5, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates (Di Bacco et al., 2006 [PubMed 16738315]).

Applications:

ELISA, IHC

Name of antibody:

SENP5

Immunogen:

Fusion protein of human SENP5

Full name:

SUMO specific peptidase 5

SwissProt:

Q96HI0

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human esophagus cancer

IHC Recommend dilution:

100-200