兔抗BCL2L2多克隆抗体

Background:

This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream PABPN1 (poly(A) binding protein, nuclear 1) gene.

Applications:

ELISA, IHC

Name of antibody:

BCL2L2

Immunogen:

Synthetic peptide of human BCL2L2

Full name:

BCL2 like 2

Synonyms:

BCLW; BCL-W; PPP1R51; BCL2-L-2

SwissProt:

Q92843

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer

IHC Recommend dilution:

20-100