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  • 兔抗BBS10多克隆抗体

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    • 品牌 : 通蔚生物
    • 目录号 : TW3197
    • 应用 : 仅用于科研使用
    • 保存条件 : 低温保存
    • 货期 : 现货
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中文名称: 兔抗BBS10多克隆抗体   

英文名称: Anti-BBS10 rabbit polyclonal antibody

别      名: Bardet-Biedl syndrome 10; C12orf58

相关类别: 一抗

储      存: 冷冻(-20℃)

宿      主: Rabbit

抗      原: BBS10

反应种属: Human

标 记 物: Unconjugate

克隆类型: rabbit polyclonal

技术规格

Background:

This gene is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by progressive retinal degeneration, obesity, polydactyly, renal malformation and mental retardation. The proteins encoded by BBS gene family members are structurally diverse and the similar phenotypes exhibited by mutations in BBS gene family members is likely due to their shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene is likely not a ciliary protein but rather has distant sequence homology to type II chaperonins. As a molecular chaperone, this protein may affect the folding or stability of other ciliary or basal body proteins. Inhibition of this protein's expression impairs ciliogenesis in preadipocytes. Mutations in this gene cause Bardet-Biedl syndrome type 10.

Applications:

ELISA, WB, IHC

Name of antibody:

BBS10

Immunogen:

Fusion protein of human BBS10

Full name:

Bardet-Biedl syndrome 10

Synonyms:

C12orf58

SwissProt:

Q8TAM1

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer

IHC Recommend dilution:

30-150

WB Predicted band size:

81 kDa

WB Positive control:

PC-3,A172 and HEPG2 cell lysates

WB Recommended dilution:

200-1000